Mesotherapy is a treatment that traditionally involves injecting a combination of vitamins, minerals, or medications into the mesoderm, which is the layer of skin beneath the epidermis. Dr. Jeffrey Rapaport of Englewood Cliff, NJ uses a variation of this technique to address various types of hair loss. Dr. Rapaport, believes that Dutasteride, which is an FDA-approved oral drug, can be an effective off label injection treatment for hair loss. Dutasteride functions by blocking the alpha reductase enzyme that produces the hormone dihydrotestosterone (DHT), which is responsible for hair loss in men and women.


According to Dr. Rapaport, Mesotherapy with Dutasteride can be used to treat hair loss while reducing systemic absorption. By injecting Dutasteride directly into the scalp, the drug can be delivered precisely to the hair follicles where it is needed. This approach minimizes the amount of medication absorbed into the bloodstream, thereby reducing the risk of side effects. To get superior results, Dr. Rapaport provides all Mesotherapy injections himself as he can better determine areas that need to be treated (max. amount is limited) and the depth of injection. Injection technique varies per individual and areas treated.


In certain cases, Dr. Rapaport also combines Mesotherapy with PRP. This combination treatment enhances the results of both of these treatments as they are synergistic.


A study published in the Journal of Cutaneous and Aesthetic Surgery examined the effectiveness of Mesotherapy with Dutasteride for the treatment of Androgenetic Alopecia, which is male-pattern hair loss. The study included 20 male patients who received six sessions of Mesotherapy with Dutasteride over six months. The treatment led to a significant increase in hair density and thickness, with minimal side effects.


Another study published in the International Journal of Trichology compared the effectiveness of Mesotherapy with Dutasteride to oral Dutasteride for the treatment of Androgenetic Alopecia. The study involved 60 male patients who were randomly assigned to receive either Mesotherapy with Dutasteride or oral Dutasteride for six months. Both treatments resulted in a significant improvement in hair density and thickness, but patients who received Mesotherapy with Dutasteride had fewer side effects.


Mesotherapy with Dutasteride is typically performed by a Hair Specialist or Dermatologist, who injects small amounts of Dutasteride into the scalp using a fine needle. The number of sessions required depends on the severity of the hair loss and the individual’s response to treatment. Treatments are usually spaced three months apart.


In conclusion, Mesotherapy with Dutasteride is a promising treatment for hair loss. It is a targeted approach that reduces the risk of side effects associated with oral medications. While more research is needed to confirm its effectiveness, early studies have shown positive results. If you are experiencing hair loss, it is advisable to schedule an appointment with a world renowned Hair Specialist, Dermatologist, Jeffrey Rapaport MD, FAAD, of Englewood Cliffs. He can assess your hair and determine the best treatment option for your individual needs.

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